腫瘤錯(cuò)配修復(fù)基因PMS2重組兔單抗

Name: 腫瘤錯(cuò)配修復(fù)基因PMS2重組兔單抗bsm-61075R
Availability: InStock

簡(jiǎn)要描述：This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gen